产品货号：
Z27887
中文名称：
THRA抗体
英文名称：
Anti-THRA Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-THRA Antibody |
| 指标别名 | AR7;c ERBA 1;c erbA alpha;EAR 7;EAR7;ERB T 1;ERBA;ERBA1;NR1A1;THRA;THRA1;THRA2;Thyroid hormone receptor alpha;V erbA related protein 7 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB |
| 基因名称 | THRA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the amino terminus of human THRA isoform 1 protein. |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This product was affinity purified from monospecific antiserum by immunoaffinity chromatography.This antibody reacts with human THRA protein.A BLAST analysis was used to suggest cross-reactivity with THRA from mouse,human and rat based on a 100% homology with the immunizing sequence.Cross-reactivity with THRA from other sources has not been determined. |
| 浓度 | 1.0mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | This antibody is suitable for Cancer,Immunology and Nuclear Signaling research.Thyroid hormone receptor alpha is a nuclear hormone receptor with high affinity for the hormone triiodo-thyronine.THRA is one of the several receptors for thyroid hormone,and has been shown to mediate the biological activities of thyroid hormone.Knockout studies in mice suggest that the different receptors,while having a certain extent of redundancy,may mediate different functions of thyroid hormone.THRA interacts with NCOA3 and NCOA6 co-activators,leading to a strong increase in transcription of target genes.THRA is localized within the nucleus and has been found to exist as 4 isoforms originating from alternative splicing variants.This antibody recognizes THRA isoform 1.Isoform 1 has a distinct C-terminus compared to isoform 2. |
| Uniprot ID | P10827-2 |
| 推荐稀释比 | ELISA:1:300,000 IHC:1:200 IF Microscopy:1:200 IP:1:100 WB:1:500 - 1:2,000 |
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